t(8;13)(p12;q12) in an atypical chronic myeloid leukaemia case
نویسندگان
چکیده
منابع مشابه
An update on chronic myeloid leukaemia.
The therapy of CML is clearly 'work in progress' Although long-term follow-up data for patients treated with STI571 are not yet available, preliminary results are encouraging. STI571 is likely to be licensed in late 2001/early 2002 and will certainly find a place in the treatment of CML. Current therapeutic considerations are summarised in Fig 2. At all stages of treatment it is vital that the ...
متن کاملChronic Myeloid Leukaemia
Chronic myeloid leukaemia (CML) is a malignant myeloproliferative disorder of haemopoietic stem cells, giving rise to abnormally elevated numbers of myeloid cells in peripheral blood and myeloid hyperplasia in bone marrow. Uncontrolled production of myeloid precursors results in increased levels of maturing granulocytes, mainly neutrophils but also eosinophils and basophils. Elevated numbers of...
متن کاملExpression Profiling of Microarray Gene Signatures in Acute and Chronic Myeloid Leukaemia in Human Bone Marrow
Background Classification of cancer subtypes by means of microarray signatures is becoming increasingly difficult to ignore as a potential to transform pathological diagnosis nonetheless, measurement of Indicator genes in routine practice appears to be arduous. In a preceding published study, we utilized real-time PCR measurement of Indicator genes in acute lymphoid leukaemia (ALL) and acute m...
متن کاملleukaemia, myelodysplastic syndromes, and chronic myeloid leukaemia
Introduction The standard approach to the diagnosis of acute leukaemia and myelodysplasia has been based on the morphology and percentage of malignant haemopoietic cells in peripheral blood and in an aspirated sample of bone marrow. The FAB group reports on acute leukaemia have emphasised the value of additional information gained from cytochemistry,' and immunological studies and cytogenetics ...
متن کاملBlastomycosis-like pyoderma in a case of chronic myeloid leukaemia.
Blastomycosis-like pyoderma, a rare skin lesion which may clinically resemble true blastomycosis, is seen in immuno-compromised individuals. We report one such case in chronic myeloid leukaemia.
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/38425